If you want to incorprate quicktime video footage into your game, you need a source for the footage. Moving images do not generate themselves unless you want to look at some trippy thing that came out of one of Kai's Power Toys.
You really have three options for this:
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Get a bunch of your friends, some costumes, and a DV camera.
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Learn Cel Animation and create a cartoon and do all the work yourself.
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Learn a 3-D animation package and do all the work yourself.
If you go the live action route, you may risk looking, well, cheesy. As a matter of fact, you probably will. I can't think of any well-done game that incorporates live-action footage.
You might be able to pull off an illustrated footage if you were talented and had access to the right kind of camera.
If you go the CG route, you will risk looking cheesy, too, simply because understanding how modellers and renderers work involves a lot of time learning. Even then you need some degree of talent to animate properly.
But really, I can't think of one game that used motion video to its benefit. Fallout came close, but it started getting old after a while. I gave up on FF VII after an hour because I was spending more time watching video than playing the game.
If you do decide to incorporate video, I would do it sparsely and make sure there's a good reason for doing so... such as a major plot event or something related to end-game logistics.
Now, what I would think would be super spiffy is a creative use of QTVR integration. If you can integrate QTVR, that is.
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--You notice that you have been turned into a pile of ashes.