I haven't had problems playing the game itself, at least with a new character. I've had problems with previously generated characters - the game freezes as soon as I try to load a previous character.
Also, on deactivating the plugin (just finished the game - big-time congrats on that plugin, it was seriously cool), the character I made for the game freezes it, and characters made before freeze it. In fact, the only ones that don't freeze it are the first ones I made, before installing the Trinity plugin.
I hadn't played PoG in a while before I got the DiD plugin, so I don't know for sure if it has anything to do with the problem, but it's a starting point.
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