It would change the nature of EV/O, which probably makes it worth trying.
Ideally you would want to have this as a running thing right the way through your plugin, so that the player would get used right at the beginning to saving their game. Very like Tomb-Raider, which certainly hasn't lost following for being brutal to idiots.
Actually, one of my friends who hadn't previously played EV, when looking at an early beta of Femme Fatale, said he thought it was unrealistic that, after having messed up a mission, you could go back to the same bar and the same person would be waiting for you. I didn't take it up at the time, but it's been niggling me.
By the way, at the end of Frozen Heart, if you fail the Black Hole missions, then you really are messed up, because half of the local universe gets eaten by the whole. This has displeased some people, and others thought it was more realistic.
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M A R T I N T U R N E R