Is this a poll for the most lethal warship, or the one that's most enjoyable to fly? That's an important distinction. A Voinian Cruiser - even stock - stomps just about everything in its path, in the crescent. It's not much fun to play, though... you end up leaning on the fire button and letting your enemies crawl all over you.
It's more fun to fly something more agile, so you can weave in and out of SAD's, nip behind asteroids to avoid Hunter missiles, etc. (Since this is a 'warship poll' I'm assuming opinions on fighters aren't allowed.) You can still get fighter-like agility from several of the ships other people have voted for here, such as the Zidara...
If money is no object though, and I think most of us have at least one hugely wealthy pilot, then there is only one choice. Igazra with engine upgrades. Preferably a few neutron turrets as well. That's the ship I chose when I set out to dominate the galaxy. With 'Maximus' I now see a little green circle at every Azdgari system, all but two Voinian systems, and I'm working my way through the Zidagar ones. The renegade bases in between have also fallen. My fleet is mostly made up of captured bounty hunters 
In anything but an Igazra, I'd have been space dust a hundred times over... or given up from boredom.
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(url="http://"http://www.geocities.com/evodude2001/home.html")Old & Unimproved: Cerberus Station!(/url)
